September 14, 2026

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Arizona Cardinals vs San Francisco 49ers: preview, kickoff time and how to follow

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Arizona CardinalsvsSan Francisco 49ers

Arizona Cardinals meet San Francisco 49ers in the NFL. It is a Week 3 fixture. Kickoff is Sunday 27 September 2026 at 4:05 pm.

Arizona Cardinals represent the National Football Conference – West; San Francisco 49ers play in the American Football Conference – West.

The score on this page updates by itself once the game starts, so there is no need to reload. When the final whistle goes the result stays here, along with Arizona Cardinals and San Francisco 49ers coverage from the newsrooms we follow.

Starters to know

Arizona Cardinals start Jacoby Brissett (QB), Jeremiyah Love (RB), Marvin Harrison Jr. (WR), Trey McBride (TE). San Francisco 49ers start Brock Purdy (QB), Christian McCaffrey (RB), Mike Evans (WR), George Kittle (TE).

Arizona Cardinals have won 0 of their last 3 games this site has covered. San Francisco 49ers have won 0 of their last 5 games this site has covered.

Bookmark this page to follow Arizona Cardinals against San Francisco 49ers, or check the full NFL schedule.

Common questions

What time is the Arizona Cardinals vs San Francisco 49ers game?
Kickoff is 4:05 PM ET, 3:05 PM CT, 2:05 PM MT, 1:05 PM PT.

Is Arizona Cardinals vs San Francisco 49ers a division game?
Arizona Cardinals represent the National Football Conference – West; San Francisco 49ers play in the American Football Conference – West.

Where can I follow the live score for Arizona Cardinals vs San Francisco 49ers?
This page updates automatically once the game begins, and shows the final result once it ends.