September 14, 2026

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The biggest questions from Week 1: Are the Giants legit? What happened to Dallas' new defense?Amazon suspends use of 21 Air, cargo carrier whose plane careened off Miami runwayShein shares fall 10% amid urgent recall of contact-lens cleaner by Australia, New ZealandCuban dance teacher ordered EU sabotage attacks from RussiaGolden again: How Team USA rallied to beat France and win the World CupRestored wetland becomes haven for rare birdsKent's shark secrets discovered in new projectSydney mayor allegedly threatened and children secretly recorded after he refused to step down, Icac hearsThe biggest questions from Week 1: Are the Giants legit? What happened to Dallas' new defense?Amazon suspends use of 21 Air, cargo carrier whose plane careened off Miami runwayShein shares fall 10% amid urgent recall of contact-lens cleaner by Australia, New ZealandCuban dance teacher ordered EU sabotage attacks from RussiaGolden again: How Team USA rallied to beat France and win the World CupRestored wetland becomes haven for rare birdsKent's shark secrets discovered in new projectSydney mayor allegedly threatened and children secretly recorded after he refused to step down, Icac hears
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Q2nd 12:27 NO 0 DET 7
Q2nd 12:04 TB 3 CIN 14
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Q2nd 12:28 ATL 7 PIT 6
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Home  /  Games

San Francisco 49ers vs Kansas City Chiefs: preview, kickoff time and how to follow

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San Francisco 49ersvsKansas City Chiefs

San Francisco 49ers meet Kansas City Chiefs in the NFL. It is a Week 16 fixture. Kickoff is Sunday 27 December 2026 at 5:25 pm.

San Francisco 49ers represent the American Football Conference – West; Kansas City Chiefs play in the National Football Conference – East.

The score on this page updates by itself once the game starts, so there is no need to reload. When the final whistle goes the result stays here, along with San Francisco 49ers and Kansas City Chiefs coverage from the newsrooms we follow.

Starters to know

San Francisco 49ers start Brock Purdy (QB), Christian McCaffrey (RB), Mike Evans (WR), George Kittle (TE). Kansas City Chiefs start Patrick Mahomes (QB), Kenneth Walker III (RB), Rashee Rice (WR), Travis Kelce (TE).

Injury watch

San Francisco 49ers: Nick Zakelj (IR. Injured Reserve), Brett Toth (IR. Injured Reserve), Austen Pleasants (IR. Injured Reserve. Expected Return Week 5), Mykel Williams (Physically Unable To Perform. Expected Return Week 5).

Kansas City Chiefs: Alohi Gilman (Questionable For Week 1 Vs. Denver), Jimmy Holiday (IR. Injured Reserve), Omarr Norman-lott (Physically Unable To Perform. Expected Return Week 6), Patrick Mahomes (Questionable For Week 1 Vs. Denver).

Head-to-head history

  • 24 August 2026 — Seattle Seahawks 9-9 Kansas City Chiefs

San Francisco 49ers have won 0 of their last 5 games this site has covered. Kansas City Chiefs have won 0 of their last 3 games this site has covered.

Bookmark this page to follow San Francisco 49ers against Kansas City Chiefs, or check the full NFL schedule.

Common questions

What time is the San Francisco 49ers vs Kansas City Chiefs game?
Kickoff is 4:25 PM ET, 3:25 PM CT, 2:25 PM MT, 1:25 PM PT.

Is San Francisco 49ers vs Kansas City Chiefs a division game?
San Francisco 49ers represent the American Football Conference – West; Kansas City Chiefs play in the National Football Conference – East.

Where can I follow the live score for San Francisco 49ers vs Kansas City Chiefs?
This page updates automatically once the game begins, and shows the final result once it ends.